Table 4.
Activity of broccoli extracts on mouse ear edema inflammation brought on by phorbol-12-myristate-13-acetate (TPA) and arachidonic acid (AA).
| Drying Method | Topical Anti-Inflammatory Effects | ||
|---|---|---|---|
| Dose (mg/ear) | %AAAA ± SEM | %AATPA ± SEM | |
| VD | 3.0 | 26.9 ± 5.8 | 37.8 ± 14.2 |
| CD | 3.0 | 46.1 ± 5.4 * | 56.1 ± 6.1 * |
| IRD | 3.0 | 42.0 ± 8.6 * | 39.8 ± 12.4 * |
| LTVD | 3.0 | 55.4 ± 4.2 * | 62.7 ± 5.4 * |
| FD | 3.0 | 34.2 ± 3.9 * | 43.2 ± 13.5 * |
| NIM | 1.0 | ↑53.4 ± 8.2 * | n.d |
| IND | 0.5 | n.d | ↑74.0 ± 13.8 * |
AATPA: topical anti-inflammatory activity against phorbol 12-myristate 13-acetate; AAAA: topical anti-inflammatory activity against arachidonic acid; NIM: nimesulide; and IND: indomethacin. n.d: not determined; ↑ maximal activity of the reference drugs. Significant differences (p < 0.05) between the samples in comparison to the negative control (100% inflammation) are indicated with an asterisk (*).