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Safety profile in the first-line setting.
| First-Line Setting, Regimen Group, No. (%) | ||||
|---|---|---|---|---|
| NIVO + IPI N = 39 |
NIVO1 + IPI3 N = 25 |
NIVO3 + IPI1 N = 14 | p Value | |
| Any treatment-related AE | 28 (72) | 18 (72) | 10 (71) | 1 |
| AE Grade ≥ 3 | 13 (33) | 12 (48) | 1 (7) | 0.013 |
Abbreviations: NIVO1 + IPI3, nivolumab 1 mg/kg + ipilimumab 3 mg/kg; NIVO3 + IPI1, nivolumab 3 mg/kg + ipilimumab 1 mg/kg; AE, adverse event.
