Table 1.
Group Name | Mouse Strain | n | Age at Insult | Insult | Time of Euthanasia |
---|---|---|---|---|---|
Prions | C57Bl/6J | 4F + 2M 1 | 6 weeks | 1% SSLOW i.p. | Terminal stage, dpi: F—166, 166, 173, 173 2 M—175, 185 |
Normal (Norm) | C57Bl/6J | 6F + 3M | 6 weeks | 1× PBS i.p. | dpi: F—197, 223, 223, 295, 346, 363; M—203, 225, 229 |
TBI-7d ipsilateral | C57Bl/6J | 3F | 12 weeks | Left hemi CCI 3 | 7 dpi (3 months old) |
TBI-7d contralateral | |||||
TBI-60d ipsilateral | C57Bl/6J | 3F | 12 weeks | Left hemi CCI | 60 dpi (5 months old) |
TBI-60d contralateral | |||||
TBI-7d Ctrl | C57Bl/6J | 3F | n/a | Sham/no CCI | 3 months old |
TBI-60d Ctrl | C57Bl/6J | 3F | n/a | Sham/no CCI | 5 months old |
MCAO-24h | C57Bl/6J | 3F | 5 month | 60 min MCAO 4 | 1 dpi |
MCAO-5d | C57Bl/6J | 3F | 5 month | 60 min MCAO | 5 dpi |
Sham-24h | C57Bl/6J | 3F | 5 month | Sham | 1 dpi |
Sham-5d | C57Bl/6J | 3F | 5 month | Sham | 5 dpi |
Aged | C57Bl/6J | 3F + 3M | n/a | Aging | 24 months old |
5XFAD | B6SJL | 3F + 3M | n/a | 5XFAD 5 mutations | 10 months old |
WT | B6SJL | 3F + 3M | n/a | No mutations | 10 months old |
1 F—females, M-males; 2 dpi—days past insult; 3 CCI—Controlled Cortical Impact; 4 MCAO—Middle Cerebral Artery Occlusion; 5 FAD—Familiar Alzheimer’s Disease.