Table 2.
Uniquely identified proteins found in at least 4 samples of the corresponding group. ICU: intensive care unit (ICU A: non-survivors, ICU B: survivors, ICU N: unknown); NW: normal ward.
| Patient Group | Relevant Processes | Protein (Gene Name) |
|---|---|---|
| Control, NW | Glycogen metabolism | PPP1R3E |
| Signaling, trafficking | CD63 | |
| Control, NW, ICU B | Signaling, trafficking, cell cycle regulation | PAPSS2, RGS7, CDK3, RAB30, PLEKHF2 |
| Focal adhesion | TNS1 | |
| ICU A+B | Acute phase | SAA1, SAA2, ORM1 |
| Antiviral response | OAS2, OAS3, PARP9, PIK3R1, DDX58 | |
| Ribosomal proteins | RPL12, RPS14, RPS4X, RPS3A | |
| Apoptosis and inflammation | PYCARD, STAT2 | |
| Nucleotide synthesis | CMPK2 | |
| Metabolism | PPT1, TFRC, BCKDK, ATP6V1D, GATM | |
| Binding activity regulation | OLFML2A, LGAL | |
| ICU A+B, NW | Acute phase, defense response | CRP, APOD, LGALS3BP, ITIH3, IGHG3, IGHM, IGKV3D-20 |
| Protein folding | FKBP4, CCDC47 | |
| Ribosomal proteins | RPS3, RPS7, RPL18, RPS18, RPS28 | |
| Cell death | CD274, HTATIP2, S100A8 | |
| Erythrocyte | CA1 | |
| Nucleic acid binding | YBX1, UBAP2L, SERBP1, PRKAR1B | |
| Metabolism | OPLAH, CP | |
| Other | ECHDC1, MAP1B, PITPNM2 |