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. 2023 Sep 1;12(17):2191. doi: 10.3390/cells12172191

Table A1.

Differently regulated proteins related to protein folding. The arrows show regulation in the first group. : upregulation (↑↑: FRR < 0.01); : downregulation (↓↓: FRR < 0.01). ICU: intensive care unit (ICU A: non-survivors, ICU B: survivors, ICU N: unknown); NW: normal ward.

Protein Name ICU A+B+N vs. Control ICU A+B+N vs. NW NW
vs. Control
ICU A
vs. ICU B
ICU B
vs. NW
Tubulin-specific chaperone A
Protein disulfide-isomerase
Heat shock protein HSP 90-alpha ↑↑
Heat shock protein HSP 90-beta ↑↑
Heat shock 70 kDa protein 1B ↑↑
60 kDa heat shock protein, mitochondrial
Clusterin
Endoplasmic reticulum chaperone BiP
Heat shock cognate 71 kDa protein
Protein disulfide-isomerase A4
Endoplasmin
T-complex protein 1 subunit alpha
Peptidyl-prolyl cis-trans isomerase B
Peptidyl-prolyl cis-trans isomerase FKBP2
Calreticulin
Endoplasmic reticulum resident protein 29
Protein disulfide-isomerase A3
Stress-induced phosphoprotein 1
Heat shock 70 kDa protein 4
Stress-70 protein, mitochondrial
T-complex protein 1 subunit zeta
T-complex protein 1 subunit epsilon
T-complex protein 1 subunit gamma
T-complex protein 1 subunit theta
T-complex protein 1 subunit delta
10 kDa heat shock protein, mitochondrial ↑↑
Peptidyl-prolyl cis-trans isomerase A
T-complex protein 1 subunit beta
Peroxiredoxin-4
Peptidyl-prolyl cis-trans isomerase FKBP5 ↑↑
Protein disulfide-isomerase A5 ↓↓
LRP chaperone MESD
Protein disulfide-isomerase A6
Hsp90 co-chaperone Cdc37
Thioredoxin domain-containing protein 5
T-complex protein 1 subunit eta
Endoplasmic reticulum resident protein 44
Protein unc-45 homolog A
UDP-glucose:glycoprotein glucosyltransferase 1
Beta-2-microglobulin
Heat shock protein 105 kDa
DnaJ homolog subfamily B member 11