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. 2023 Sep 1;15(17):4365. doi: 10.3390/cancers15174365

Table 1.

Patient characteristics.

Total Cohort
n = 260
Preoperative Quest.
n = 200
Postoperative Quest.
n = 88
112 Male/
148 Female
Male
n = 91
Female
n = 109
Male
n = 37
Female
n = 51
Age 52.60 +/− 12.7 53.0 +/− 12.4 50.59 +/− 11.7 50.43 +/− 11.6
Koos
1
2
3
4

43 (16.5%)
76 (29.2%)
81 (31.2%)
60 (23.1%)

16 (17.6%)
36 (39.6%)
26 (28.6%)
13 (14.3%)

26 (23.9%)
31 (28.4%)
33 (30.3%)
19 (17.4%)

H = 0.02
p = 0.892

1 (2.7%)
5 (13.5%)
16 (43.2%)
15 (40.5%)

1 (2.0%)
9 (17.6%)
20 (39.2%)
21 (41.2%)

H = 0.01
p = 0.913
Side
Left/
Right

137 (52.7%)
123 (47.3%)

56 (61.5%)
35 (38.5%)

55 (50.5%)
54 (49.5%)

X2 = 2.47
p = 0.116

18 (48.6%)
19 (51.4%)

21 (41.2%)
30 (58.8%)

X2 = 0.49
p = 0.486
Operation
Yes
No

165 (63.5%)
95 (36.5%)

45 (49.5%)
46 (50.5%)

50 (45.9%)
59 (54.1%)

X2 = 0.04
p = 0.847

37 (100%)
0

51 (100%)
0

X2 = 0
p = 1
TSD/TSS 1.23 +/− 2.3 y 1.16 +/− 2.2 y H = 0.25
p = 0.615
1.48 +/− 2.1 y 2.37 +/− 3.1 H = 0.14
p = 0.137
HB
I
II
III
IV
V


89 (97.8%)
2 (2.2%)
0
0
0

104 (95.4%)
5 (4.6%)
0
0
0

H = 83
p = 0.361

20 (54.1%)
7 (18.9%)
5 (13.5%)
4 (10.8%)
1 (2.7%)

28 (54.9%)
11 (21.6%)
5 (9.8%)
3 (5.9%)
4 (7.8%)

H = 0.01
p = 0.930
EOR
GTR
STR
PR

64 (72.7%)
19 (21.6%)
5 (5.7%)

-
-
-

-
-
-

25 (67.6%)
8 (21.6%)
4 (10.8%)

39 (76.5%)
11 (21.6%)
1 (2.0%)

X2 = 3.19
p = 0.203
SF-36
physical function
role physical
bodily pain
general health
vitality
social function
role emotional
mental health


89.78 ± 17.7
75.27 ± 36.6
76.45 ± 27.8
63.87 ± 17.5
58.52 ± 19.9
77.20 ± 25.2
73.35 ± 40.1
69.71 ± 19.3

81.06 +/− 24.2
64.45 +/− 42.3
66.58 +/− 30.8
59.73 +/− 17.6
52.16 +/− 20.5
70.64 +/− 25.8
65.14 +/− 41.7
64.62 +/− 17.9

p = 0.001 *
p = 0.067
p = 0.023 *
p = 0.097
p = 0.032 *
p = 0.053
p = 0.089
p = 0.043 *

86.89 +/− 16.6
72.16 +/− 33.6
80.46 +/− 27.0
66.08 +/− 19.6
59.65 +/− 16.7
78.11 +/− 21.9
84.01 +/− 29.9
75.89 +/− 18.7

78.76 +/− 21.7
60.00 +/− 41.2
71.57 +/− 30.2
65.24 +/− 19.2
55.53 +/− 24.0
73.97 +/− 26.7
70.59 +/− 43.5
69.65 +/− 20.5

p = 0.079
p = 0.256
p = 0.132
p = 0.879
p = 0.425
p = 0.579
p = 0.251
p = 0.129
PANQOL
anxiety
facial
general health
balance
hearing
energy
pain
Total


70.54 ± 22.9
90.57 ± 14.2
56.32 ± 19.0
76.69 ± 22.0
63.46 ± 22.5
71.98 ± 21.5
70.05 ± 28.9
71.37 ± 15.6

59.98 +/− 22.1
87.92 +/− 14.3
54.0 +/− 15.3
67.05 +/− 25.7
66.17 +/− 21.0
63.80 +/− 24.2
63.07 +/− 30.2
66.10 +/− 14.6

p = 0.001 *
p = 0.129
p = 0.267
p = 0.008 *
p = 0.332
p = 0.015 *
p = 0.086
p = 0.006 *

78.55 +/− 22.8
81.67 +/− 20.6
61.49 +/− 19.6
73.76 +/− 22.2
63.34 +/− 18.0
72.07 +/− 20.5
81.76 +/− 24.0
73.21 +/− 14.3

70.21 +/− 19.4
69.73 +/− 25.9
66.10 +/− 19.2
62.91 +/− 21.7
58.99 +/− 24.9
64.99 +/− 25.6
62.42 +/− 33.4
64.29 +/− 17.8

p = 0.027 *
p = 0.027 *
p = 0.420
p = 0.008 *
p = 0.468
p = 0.242
p = 0.006 *
p = 0.016 *
DHI 9.65 ± 16.3 18.26 +/− 20.8 p = 0.001 * 12.92 +/− 16.7 24.39 +/− 22.7 p = 0.011 *
THI 19.41 ± 21.1 21.71 +/− 21.5 p = 0.431 15.51 +/− 18.1 20.20 +/− 22.3 p = 0.432
HHI 20.59 ± 20.9 19.43 +/− 22.2 p = 0.473 29.68 +/−19.8 27.65 +/−23.1 p = 0.475
FDI
physical function
social function

98.74 ± 10.5
97.89 ± 12.1

99.27 +/− 3.3
97.87 +/− 8.1

p = 0.319
p = 0.402

88.24 +/−16.5
88.22 +/−16.3

84.31 +/− 19.6
84.47 +/− 20.4

p = 0.382
p = 0.491

* p-values indicate significance comparing male and female by a Chi-square (X2) or Kruskal–Wallis test (H). FDI: Facial Disability Index; DHI: Dizziness Handicap Inventory; HB: House-Brackmann scale; HHI: Hearing Handicap Inventory; EOR: extent of resection; GTR: gross total resection; PANQOL: Penn Acoustic Neuroma Quality-of-Life Scale; PR: partial resection; SF-36: general Short-Form Health Survey; STR: subtotal resection; THI: Tinnitus Handicap Inventory; TSD: time since diagnosis; TSS: time since surgery; FDI: Facial Disability Index.