Table 3.

The major types of genetic mutation or deletion cause other myopathies with mitochondria phenotypes.

Myopathy	Gene of Mutation	nDNA/mtDNA	Muscle and Mitochondria Phenotypes	Reference
dermatomyositis	Unknown		Increase the proportion of SDH staining positive fiber and Cox staining negative fiber.	[188]
Pompe Disease	GAA	nDNA	Short and fragmented mitochondria reduce mitochondria respiration activity and ATP generation. Increase ROS generation. Mitochondria calcium overload. Increase expression of mitochondria dynamic-related protein but reduce mitophagy activity.	[189,192]
Metabolic myopathy	MIEF2	nDNA	Elongated mitochondria, aberrant mitochondrial cristae organization.	[190]
Dysferlinopathy	DYSF	nDNA	Decrease complex I, III, and IV protein level and activity, decrease cell ATP level.	[191]