Table 1.

Different types of NF1 microdeletions with their frequencies and the molecular genetic methods suitable for their classification.

Microdeletion Type	Type-1	Type 2	Type 3	Atypical
Frequency	70–80%	~10%	1–4%	10–20%
Suitable method for appropriate deletion classification	MLPA Probemix P122-D2 NF1-area or microarray analysis	Microarray analysis	Microarray analysis	Microarray analysis
Affected genes	14 protein coding and 5 miRNA	13 protein coding and 5 miRNA	9 protein coding and 5 miRNA	Heterogeneous