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. 2023 Aug 23;24(17):13133. doi: 10.3390/ijms241713133

Figure 1.

Figure 1

BTK-p80 and BTK-p65 are differentially expressed in tumor samples of head and neck tumor tissue. Tissue microarray (TMA) was stained for BTK-p80 using the BTK 7F12H4 antibody obtained from Santa Cruz, which detects BTK-p80 only [31] (A,B), or for BTK-p65 using the BTK BN30 antibody [22] (C,D). Quantification of the immunohistochemical staining is depicted. Percentages of positively stained cases were grouped according to inflamed, benign, malignant, and metastatic tissue. (B,D) BTK expression was analyzed in different head and neck tumor entities like adenoid cystic carcinoma (ACC) and squamous cell carcinoma (HNSCC). Overall, the TMA contained 48 cases in duplicate: 3 cases of inflamed, 17 of benign, 25 of malignant, and 3 of metastatic tissues.