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Hierarchical clustering in the heatmap shows differentially expressed genes between HNSCC cells (UDSCC 1, 5, and 6) treated with 20 µM AVL292 or 0.1% DMSO as a control for 72 h. Cells were either cultured under 2D conditions or on ULA surface plates as a three-dimensional culturing system. Data analysis was performed in R (4.0.2) using the IDE Rstudio (1.3.1056).
