Table 2.
Prognostic Factor | Mammaglobin-A Expression |
---|---|
Tumor Subtype and Stage | Variable expression with positivity rates ranging from 59% to 100% for lobular breast carcinomas and 25% to 94% for invasive breast carcinomas |
Hormone Receptor Status | Elevated levels correlate with estrogen receptor (ER) and progesterone receptor (PR) status |
Tumor Grade | High tumor grade associated with overexpression of human mammaglobin (hMAM) |
Cell Proliferation | Higher Ki-67 proliferation index observed in hMAM-positive invasive breast cancer |
Peritumoral Expression | Presence detected, suggesting a possible link with local invasion, metastasis, and aggressive disease phenotypes |