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. 2023 Aug 29;24(17):13407. doi: 10.3390/ijms241713407

Table 2.

Mammaglobin-A expression and correlation with breast cancer prognostic factors.

Prognostic Factor Mammaglobin-A Expression
Tumor Subtype and Stage Variable expression with positivity rates ranging from 59% to 100% for lobular breast carcinomas and 25% to 94% for invasive breast carcinomas
Hormone Receptor Status Elevated levels correlate with estrogen receptor (ER) and progesterone receptor (PR) status
Tumor Grade High tumor grade associated with overexpression of human mammaglobin (hMAM)
Cell Proliferation Higher Ki-67 proliferation index observed in hMAM-positive invasive breast cancer
Peritumoral Expression Presence detected, suggesting a possible link with local invasion, metastasis, and aggressive disease phenotypes