γH2AX	phosphorylated H2A histone member X
53BP1	tumour suppressor p53-binding protein 1
ADP	adenosine diphosphate
ATM	ataxia telangiectasia mutated
ATR	ataxia telangiectasia and Rad3 related
BER	base excision repair
BRCA1	breast cancer type 1 susceptibility protein
CDK2	cyclin-dependent kinase 2
CHFR	checkpoint with forkhead and RING finger domain protein
c-Met	mesenchymal-epithelial transition factor
CRPC	castration-resistant prostate cancer
DBD	DNA-binding domain
DCK	deoxycytidine kinase
DHT	dihydrotestosterone
DNA	deoxyribonucleic acid
DNA-PK	DNA-dependent protein kinase
DSB	double-strand break
EBS	ETS-binding site
ECM	extracellular matrix
Ehf	ETS homologous factor
ELF	E74-like factor
EMT	epithelial–mesenchymal transition
ER71	Ets-related protein 71
Erf	Ets-2 repressor factor
ERG	ETS-related gene
ERK-2	extracellular signal-regulated kinase-2
ESE	epithelium-specific Ets
ETS	E-twenty-six specific
Etv	ETS translocation variant
Fev	fifth Ewing variant
Fli1	friend leukaemia integration 1
GABP	GA-binding protein
HR	homologous recombination
MLL	methyltransferases mixed-lineage leukaemia
MMP	matrix metalloproteinase
MRN	Mre11-Rad50-Nbs1
NAD+	nicotinamide adenine dinucleotide
NADPH	nicotinamide adenine dinucleotide phosphate
NER	nucleotide excision repair
NHEJ	non homologous end joining
NR	nuclear receptors
PAR	poly(ADP-ribose) polymers
PARG	poly(ADP-ribose) glycohydrolase
PARP-1	poly(ADP-ribose) polymerase-1
PARPi	poly(ADP-ribose) polymerase inhibitor
PARylation	poly(ADP-ribosyl)ation
PDEF	prostate-derived Ets factor
PD-L1	programmed cell death-ligant 1
PEA3	polyomavirus enhancer activator 3 homolog
RNA	ribonucleic acid
RNF146	RING finger protein 146
ROS	reactive oxygen species
Spdef	SAM pointed domain-containing Ets transcription factor
SSB	single-strand break
TCF	ternary complex factor
TMPRSS2	transmembrane protease serine 2
WT	Wild type