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IgG1 and IgG2a titers of mice inoculated with rabies vaccine via SC, IM, IP and ID routes. Mice (n = 6) were immunized twice at a 1-week interval. Serum samples were collected at 2 weeks after prime immunization and IgG1 or IgG2a antibody titers against rabies were evaluated by ELISA. Statistical difference of IgG1 titer and IgG2a titer: ns, not significant; * p < 0.05.
