ADME	Absorption–distribution–metabolism–excretion
AhR	Aryl hydrocarbon receptor
AIME	Alginate immobilization of metabolic enzymes
AR	Androgen receptor
ATP	Adenosine triphosphate
BrdU	Tritiated thymidine, 5-bromo-2’-deoxyuridine
BW	Body weight
CAR	Constitutive androstane receptor
CCP	Cell cycle proliferation
CFSE	Carboxyfluorescein succinimidyl ester
CYP	Cytochrome P450
14C-Thy	14Carbon-labelled thymidine
ECHA	European Chemicals Agency
EFSA	European Food Safety Authority
EGF	Epidermal growth factor
ER	Estrogen receptor
FANFT	N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide
FFPE	Formalin-fixed paraffin-embedded
GARDTM	Genomic Allergen Rapid Detection (in vitro platform for safety assessment of chemicals)
GIT	Gastrointestinal tract
H2O2	Hydrogen peroxide
3H-Thy	Tritiated thymidine
HTTr	High-throughput transcriptomics
IATA	Integrated approaches to testing and assessment
ICH	International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use
i.p.	Intraperitoneal
IPCS	International Program on Chemical Safety
i.v.	Intravenous
Ki-67	Nuclear antigen expressed in all phases of the cell cycle and mitosis
LW	Liver weight
MIE	Molecular initiating event
MoA	Mode of action
MSigDB	Molecular Signatures Database
NAMs	New approach methods
NGTxC	Non-genotoxic carcinogens
OECD	Organization for Economic Cooperation and Development
PBK	Physiologically based kinetic
PCNA	Proliferating cell nuclear antigen
PPARα	Peroxisome proliferator-activated receptor alpha
PXR	Pregnane X receptor
QSAR	Quantitative structure activity relationship
ReCAAP	Rethinking Carcinogenicity Assessment for Agrochemicals Project
s.c.	Subcutaneous
TCGA	The Cancer Genome Atlas
TG	Test guideline
TGx-DDI	Toxicogenomic DNA damage-inducing
T-hormone	Thyroid hormone
TSH	Thyroid-stimulating hormone
UDP-GT	Uridine 5’-diphospho-glucuronosyl transferase
US FDA	United States Food and Drug Administration
WHO	World Health Organization
Wyeth (WY)	4-chloro-6-(2,3-xylidino)-pyrimidilnylthioacetic acid