Table 4.

The effect of AML cell viability of the V-ATPase inhibitors bafilomycin A1 10 nM and concanamycin A 10 nM: a summary of the overall results. AML cells derived from 80 patients were tested after 48 h of incubation in cytokine-supplemented medium with and without drugs. The results are presented as the percentage of viable Annexin⁻PI⁻ cells, and the table summarized the overall results for the 80 patients (median and variation range). The Wilcoxon’s test for paired samples was used for all statistical comparisons, and Pearson’s test was used for correlation analyses.

Drugs Added	Viability (%)		p-Values for the Various Statistical Comparisons
	Median	Range	Versus Drug- Free Control	Versus Concanamycin	Versus Cytarabine	Correlation with Control
Drug-free control	54.1	2.0–97.2
Bafilomycin A1 10 nM	51.0	0.6–95.2	<0.00001	<0.00001	0.00112	<0.00001 (r = 0.98)
Concanamycin A 10 nM	16.4	1.9–97.2	<0.00001	-	<0.00001	<0.00001 (r = 0.74)
Cytarabine 10 nM	53.1	2.6–97.9	<0.00001	<0.00001	-	<0.00001 (r = 0.99)