Figure 3.

Effect of HT hybrids on BACE-1 activity. The residual BACE-1 activity was determined in the absence or in the presence of the indicated concentration of HT1 (filled circles), HT1a (empty circles), HT2 (filled lozenges), HT3 (filled squares), HT3a (empty squares), HT4 (filled triangles), and HT4a (empty triangles), as reported in the Material and Methods section. Data points are shown as mean percentage values ± sd calculated with respect to the activity measured in the absence of the hybrid on at least 3 different determinations.