A diagnostic algorithm for Crohn’s disease. Imaging and endoscopic modalities algorithm for the diagnosis of Crohn’s disease with indication, risks, and benefits of each modality, created and adapted from most recent American College of Gastroenterology (ACG), European Crohn’s and Colitis Organization (ECCO), and British Society of Gastroenterology (BSG) guidelines [1,10,11]. * Guidelines were similar across most areas other than Small Bowel Ultrasound (SBUS) use—not part of ACG clinical guidelines. MRE: magnetic resonance enterography, CTE: computed topography enterography. CD: Crohn’s disease.