Table 1.
Comparison of aSAH Patients According to Prognosis at 3 Months (mRS Score 0–2 Vs 3–6)
| Patient Characteristics | mRS Score at 3 Month | p value | |
|---|---|---|---|
| 0–2 (n=320) | 3–6 (n=88) | ||
| Age, yrs, mean±SD | 53.61±11.90 | 61.32±11.72 | <0.001 |
| Female, n (%) | 207 (64.7) | 52 (59.1) | 0.334 |
| Prior medical history | |||
| Hypertension, n (%) | 162 (50.6) | 60 (68.2) | 0.003 |
| Hyperlipidemia, n (%) | 23 (7.2) | 5 (5.7) | 0.621 |
| Diabetes mellitus, n (%) | 19 (5.9) | 6 (6.8) | 0.760 |
| Heart Disease, n (%) | 18 (5.6) | 13 (14.8) | 0.004 |
| Aneurysm characteristics | |||
| Posterior circulation, n (%) | 32 (10.0) | 10 (11.4) | 0.709 |
| Neurological data/score | |||
| Early seizures, n (%) | 13 (4.1) | 9 (10.2) | 0.023 |
| Early loss of consciousness, n (%) | 66 (20.6) | 44 (50.0) | <0.001 |
| WFNS grade 4–5, n (%) | 38 (11.9) | 45 (51.1) | <0.001 |
| mFS grade 3–4, n (%) | 206 (64.4) | 75 (85.2) | <0.001 |
| Graeb score 5–12, n (%) | 17 (5.3) | 15 (17.0) | <0.001 |
| SEBES score 3–4, n (%) | 138 (43.1) | 30 (34.1) | 0.127 |
| Acute hydrocephalus, n (%) | 126 (39.4) | 42 (47.7) | 0.159 |
| Laboratory values on admission | |||
| IBIa, median (IQR) | 21.61 (9.11–58.66) | 46.88 (13.26–220.80) | <0.001 |
| N/L, median (IQR) | 10.91 (6.97–15.79) | 14.37 (9.01–21.89) | 0.001 |
| C-reactive protein b, median (IQR) | 2.07 (0.92–5.46) | 3.93 (1.47–11.91) | 0.001 |
| Neutrophils c, median (IQR) | 10.66 (8.11–12.98) | 13.18 (9.67–17.10) | <0.001 |
| Lymphocytes d, median (IQR) | 0.99 (0.71–1.35) | 0.89 (0.70–1.37) | 0.279 |
| Glucose e, median (IQR) | 7.40 (6.48–8.90) | 8.63 (7.30–10.18) | <0.001 |
| Hemoglobin f, median (IQR) | 141 (129–152) | 143 (134–151) | 0.391 |
| Leukocytes g, median (IQR) | 12.16 (9.68–14.25) | 15.06 (11.63–18.50) | <0.001 |
| Platelet h, median (IQR) | 226 (192–269) | 223 (179–281) | 0.946 |
| Monocytes i, median (IQR) | 0.38 (0.27–0.52) | 0.54 (0.39–0.72) | <0.001 |
| Treatment modality | 0.092 | ||
| Surgical clipping, n (%) | 153 (47.8) | 51 (58.0) | |
| Endovascular coiling, n (%) | 167 (52.2) | 37 (42.0) | |
| In-hospital complications | |||
| Delayed cerebral ischemia, n (%) | 66 (20.6) | 50 (56.8) | <0.001 |
| Intracranial infection, n (%) | 31 (9.7) | 13 (14.8) | 0.173 |
| Hypoproteinemia, n (%) | 98 (30.6) | 49 (55.7) | <0.001 |
| Pneumonia, n (%) | 98 (30.6) | 69 (78.4) | <0.001 |
| Deep Vein Thrombosis, n (%) | 38 (11.9) | 33 (37.5) | <0.001 |
Notes: aUnit of measurement: mg/L. bUnit of measurement: mg/L. cUnit of measurement: 109/L. dUnit of measurement: 109/L. eUnit of measurement: mg/L. fUnit of measurement: g/L. gUnit of measurement: 109/L. hUnit of measurement. iUnit of measurement: 109/L. As indicated by the bold font, the p value reached statistical significance.
Abbreviations: aSAH, aneurysmal subarachnoid hemorrhage; mRS, modified Rankin Scale; ASMD, Absolute Standardized Mean Difference; WFNS, world federation of neurological societies; mFS, modified Fisher; SEBES, subarachnoid hemorrhage early brain edema score; IBI, inflammatory burden index; N/L, neutrophils to lymphocytes ratio.