Table 2.
The effect of vitamin D supplementation method on 25(OH)D concentration (nmol/L) using network meta-analysis.
| Detecting time | Total dose, IU | Average dose, IU/day | Daily | Weekly | Monthly | |||
|---|---|---|---|---|---|---|---|---|
| N | Pooled MD (95%CI) | N | Pooled MD (95%CI) | N | Pooled MD (95%CI) | |||
| 2 Months | 36,000 | 600 | 2 | 38 (19,62) | – | – | 2 | 19 (0,41) |
| 100,000 | 1,666 | 4 | 33 (15,50) | 2 | 24 (−5,52) | 5 | 28 (13,44) | |
| 200,000 | 3,333 | 4 | 34 (4,64) | 5 | 49 (22,75) | – | – | |
| 3 Months | 90,000 | 1,000 | 18 | 31 (21,40) | 3 | 21 (−2,43) | – | – |
| 180,000 | 2,000 | 18 | 38 (28,47) | – | – | 4 | 32 (11,54) | |
| 300,000 | 3,333 | 11 | 34 (19,49) | 9 | 34 (18,50) | – | – | |
| 600,000 | 6,666 | 2 | 74 (28,120) | 22 | 63 (49,77) | – | – | |
| 6 Months | 300,000 | 1,666 | 6 | 33 (23,44) | – | – | 4 | 25 (13,38) |
| 600,000 | 3,333 | 2 | 54 (29,79) | 13 | 43 (34,53) | – | – | |
| 12 Months | 720,000 | 2,000 | 6 | 41 (32,51) | – | – | 4 | 24 (13,34) |
N indicates the number of trials. MD indicates a mean difference. The number in bold indicates its value of p is less than 0.05.