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. 2023 Sep 4;15:333–347. doi: 10.2147/JEP.S421338

Table 6.

Effect of Vernonia Auriculifera on Serum Biochemical Parameters in Dimethylhydrazine-Induced Colorectal Cancer

Groups Triglyceride (mg/dl) Total Cholesterol (mg/dl) Total Protein (mg/dl)
Normal control 59.82 ± 4.25 55.57 ± 1.24 6.54 ± 0.08
DMH20 89.25 ± 8.0a** 71.43 ± 5.84a* 5.60 ± 0.14a*
ASA60 61.33 ± 5.05b** 55.82 ± 0.84b* 6.27 ± 0.22
Pre-initiation phase
PIV100 62.73 ± 1.62 b* 58.35 ± 1.27 5.75 ± 0.17
PIV200 63.20 ± 4.83 b* 59.95 ± 1.77 5.85 ± 0.14
PIV400 60.00 ± 2.68 b** 57.33 ± 4.07b* 6.10 ± 0.16
Post-initiation phase
POV100 67.97 ± 2.82 63.52 ± 3.22 5.56 ± 0.22a**
POV200 65.55 ± 6.36 b* 61.20 ± 2.05 5.63 ± 0.20a*
POV400 63.77± 6.43 b* 58.72 ± 2.69 5.87 ±0.20

Notes: Data are expressed as mean ± standard error of the mean (SEM); n=6; Compared to normal control; bCompared to DMH20; ASA60, Aspirin 60 mg/kg; DMH20, dimethylhydrazine 20 mg/kg; PIV and POV; Pre-initiation and Post initiation V. auriculifera at 100, 200, and 400 mg/kg, respectively; *p<0.05; **p<0.01.