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Sequence alignment between human 5-HT2AR (Uniprot entry P28223) and 5-HT2BR (UniProt entry P41596) performed by Clustal Omega [66]. Special characters meanings: * (Asterix) positions with a single, fully conserved residue; “:” (colon) positions with conservation between amino acid groups of similar properties; “.” (period) positions with conservation between amino acid groups of weakly similar properties.
