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. 2023 Sep 1;12(17):5692. doi: 10.3390/jcm12175692

Figure 1.

Figure 1

Schematic diagram illustrating two modes of action of hydroxyurea: (1) hydroxyurea elevates HbF levels in red blood cells and (2) increases the bioavailability of NO, inhibiting vasoconstriction and vaso-occlusion.