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. 2023 Aug 29;28(17):6328. doi: 10.3390/molecules28176328

Table 1.

Composition of plasmalogen in different mammalian organs and tissues.

Species Organs and Tissues PlsEtn
(% EtnGpl)
PlsEtn
(% Total PL)
PlsCho
(% ChoGpl)
PlsCho
(% Total PL)
Plasmalogen
(% Total PL)
Plasmalogen
(% Wet Weight)
Refs.
Human
Whole brain 58 20, 22 1 0.8, 0.9 22 [17,18]
Brain prefrontal cortex 49 0.7 [19]
Brain temporal cortex 46 0.5
Brain gray matter 49 19 0.1 19 0.4, 0.7 [20,21]
Brain gray matter—frontal cortex 57 20 0.7 [10,22]
Brain gray matter—parietal cortex 58 19 0.7
Brain gray matter—temporal cortex 56
Brain gray matter—cerebellum 63
Brain white matter 83, 86 33 2.6, 0.4 0.1 37 1.1, 1.8 [19,20,21]
Brain white matter—frontal cortex 84 29 2 [10,22]
Brain white matter—parietal cortex 81 36 2.7
Brain white matter—temporal cortex 83
Brain white matter—cerebellum 78
Myelin 91 36 0.5 0.1 43 7.0 [20]
Heart 53, 51 17, 14, 15 26, 36 14, 11, 15 32, 29 [17,18,23]
Skeletal muscle 48, 63 14, 15 19, 16 6.5, 9.7 0.2 [17,18,22,23]
Cultured artery endothelial cells 48 13 1.9 0.9 [24]
Cultured vein endothelial cells 34 8.7 0.2 0.1
Kidney 46 14 5 4.7 [17,18]
Liver 8 4.7 3 3.4
Colon 36 11 9 3.9 19, 15 0.1, 0.1 [22,25]
Lens 70 14 [26]
Neutrophils 68 3.6 [27]
Eosinophils 72 4 [28]
Red blood cells 58, 48, 46 17,14, 9 8 2.8 20, 14, 9 [29,30,31]
Plasma 53 2.5 5.5 5.2 7.7 [32]
Serum 5.9 4.5 10 [33]
HDL 55 6.4, 5 4.7 4.5, 4 11, 10 [32,34]
LDL 60 5.9, 4 4.4 4.2, 4 10, 10
Platelet 54 0.8 [35]
Cultured macrophage 62 8.8 [36]
Spermatozoa 9 3 12 [37]
Rat
Whole brain 66 1.7 1 [19,22]
Cortex 22 [38]
Cerebellum 26
Hippocampus 23
Brainstem 32
Midbrain 24
Brain synaptic vesicles 16 [39]
Heart 28 9.8 5.7 2.4 12 0.2 [22,40]
Cultured heart sacrolemma 43 19 [41]
Lung 42 1.6 16 0.3 [22,42]
Kidney 20 2.3 12 0.3
Liver 3.3 0.4 3.4 0.07
Red blood cells 65 16 0.9 0.5 16 [13]
Plasma 51, 36 0.4 0.5 0.4 0.8 [13,43]
HDL 46 2.4 [43]
LDL 32 1.9
VLDL 14 1.6
Mature spermatozoa 42 52 38 [44]
Mouse
Whole brain 47 1.2 [19]
Cortex 46 [10,22]
Cerebellum 53
Heart 24 8.2 62 31 39 [45]
Dog
Heart sarcolemma 73 16 57 37 53 [46]
Rabbit
Whole brain 26 1.3 [22]
Heart 32 0.6
Lung 14 0.3
Kidney 14 0.3
Liver 2 0.06
Macrophage 61 13 6 2 15 [47]
Guinea pig
Whole brain 0.9 [21]

The composition of this table was primarily created by referring to [14,15] with their permission. For references [20,22], the values displayed in the table were converted from the data in the literature. Average molecular weight of glycerophospholipids used was 775. ChoGpl, choline glycerophospholipid; EtnGpl, ethanolamine glycerophospholipid; HDL, high-density lipoprotein; LDL, low-density lipoprotein; PL, phospholipid; PlsCho, choline plasmalogen; PlsEtn, ethanolamine plasmalogen; VLDL, very-low-density lipoprotein.