Table 1.
Clinical and pathological features of patients with IPMN and co-occurring carcinoma
| Carcinoma | Total cases (adj-IPMN/dist-IPMN) | Gender | Age | Location carcinoma/adj-IPMN | Location dist-IPMN | Cancer | IPMN | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||||||||||||
| T | N | Grade | Size (cm) | Grade | Type | Subtype | |||||||||||||
|
| |||||||||||||||||||
| Ductal adenocarcinoma | 56 (53/42) | M 63.6% (35) | 70.2 | Head | 62.5% (35) | 36% (20) | T1 | 10.7% (6) | NO | 30.4% (17) | 1 | 3.6% (2) | 2.9 | LGD | 19.6% (11) | BD | 57.4% (27) | Gastric | 61.8% (34) |
| F 36.4% (21) | (+/−10.8) | Neck | 8.9% (5) | 28% (15) | T2 | 39.3% (22) | N1 | 69.6% (39) | 2 | 62.5% (35) | (+/−2.5) | HGD | 80.4% (45) | MD | 29.8% (14) | Intestinal | 7.2% (4) | ||
| Body | 7.1% (4) | 20% (11) | T3 | 46.4% (26) | 3 | 26.8% (15) | Mixed | 12.8% (6) | Pancreatobiliary | 23.6% (13) | |||||||||
| Tail | 14.3% (8) | 12% (6) | T4 | 3.6% (2) | 4 | 3.6% (2) | Oncocytic | 7.2% (4) | |||||||||||
| Multifocal | 5.3% (3) | - | |||||||||||||||||
| Colloid carcinoma | 13 (11/9) | M 76.9% (10) | 62.5 | Head | 92.3% (12) | 50% (6) | T1 | 53.8% (7) | NO | 92.3% (12) | 1 | 61.5% (8) | 4.9 | LGD | 0% (0) | BD | 7.7% (1) | Gastric | 0% (0) |
| F 23.1% (3) | (+/−11.9) | Neck | 0% (0) | 16.7% (2) | T2 | 23.1% (3) | N1 | 7.7% (1) | 2 | 38.5% (5) | (+/−1.94) | HGD | 100% (13) | MD | 69.2% (9) | Intestinal | 100% (13) | ||
| Body | 7.7% (1) | 16.7% (2) | T3 | 23.1% (3) | 3 | 0% (0) | Mixed | 23.1% (3) | Pancreatobiliary | 0% (0) | |||||||||
| Tail | 0% (0) | 16.7% (2) | T4 | 0% (0) | 4 | 0% (0) | Oncocytic | 0% (0) | |||||||||||
| Multifocal | 0% (0) | - | |||||||||||||||||
| Carcinoma of the ampullary region | 7 (6/5) | M 42.8% (3) | 74.1 | Head | 100% (7) | 100% (5) | T1 | 0% (0) | NO | 0% (0) | 1 | 0% (0) | 1.1 | LGD | 71.4% (5) | BD | 71.4% (5) | Gastric | 85.7% (6) |
| F 57.2% (4) | (+/− 8.5) | Neck | 0% (0) | 0% (0) | T2 | 0% (0) | N1 | 100% (7) | 2 | 57.1% (8) | (+/−0.19) | HGD | 28.6% (2) | MD | 14.3% (1) | Intestinal | 0% (0) | ||
| Body | 0% (0) | 0% (0) | T3 | 71.4% (5) | 3 | 42.8% (6) | Mixed | 14.3% (1) | Pancreatobiliary | 14.3% (1) | |||||||||
| Tail | 0% (0) | 0% (0) | T4 | 28.8% (2) | 4 | 0% (0) | Oncocytic | 0% (0) | |||||||||||
| Multifocal | 0% (0) | 0% (0) | |||||||||||||||||
| Significance* | ns | ns | ns | ns | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.009 | <0.001 | ||||||||
*
Tests were performed via ANOVA test for continuous variables or Fisher-Exact test for categorical variables.
ANOVA, analysis of variance; BD, branch duct; HGD, high grade dysplasia; IPMN, intraductal papillary mucinous neoplasm; LGD, low grade dysplasia; MD, main duct.