Table 2.
Associations of low and high TSH levels with markers of renal function.
| TSH < 0.49 mIU/L # β (95%-CI) |
TSH ≥ 3.29 mIU/L # β (95%-CI) |
|
|---|---|---|
| eGFR (CKD-EPI); mL/min | 2.26 (1.14; 3.83) * | −3.71 (−5.16; −2.25) * |
| eGFR (FAS); mL/min | 2.44 (1.16; 3.71) * | −4.14 (−5.78; −2.49) * |
| Odds ratio (95%-CI) | Odds ratio (95%-CI) | |
| eGFR (CKD-EPI) < 60 mL/min | 0.88 (0.65; 1.20) | 1.30 (0.82; 2.05) |
| eGFR (FAS) < 60 mL/min | 0.78 (0.59; 1.03) | 1.26 (0.84; 1.88) |
| ACR ≥ 30 mg/g | 0.96 (0.75; 1.22) | 1.35 (0.97; 1.88) |
# compared to TSH in the range; CI, confidence interval; * p < 0.05. Estimates are derived from linear (continuous outcomes) and logistic regression (dichotomous outcomes) models adjusted for age, sex, smoking status, intake of thyroid medication, and study.