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. 2023 Sep 1;15(17):3829. doi: 10.3390/nu15173829

Figure 4.

Figure 4

HFHC diet and PC altered BAs metabolic homeostasis. (a,b): PCoA analysis of fecal BAs profile at week 3 (a) or 6 (b) in the HFHC−PC, LFLC−PC, and LFLC−NC groups. (c): The relative concentration of colonic total CDCA, CA, β-MCA, LCA, DCA, ursodeoxycholic (UDCA), hyodeoxycholic acid (HDCA), and GDCA in the HFHC−PC, LFLC−PC, and LFLC−NC groups at week 6, respectively. (d): The relative concentration of feces total CDCA, CA, β-MCA, LCA, DCA, UDCA, HDCA, GDCA, and TLCA in the HFHC−PC, LFLC−PC, and LFLC−NC groups at weeks 3 and 6. (e–k): Relative mRNA expression of CYP7A1 (e), CYP8B1 (f), CYP7B1 (g), CYP27A1 (h), FXR (i), and BSEP (j) in liver, and ASBT (k) in the colon. * p < 0.05, ** p < 0.01.