Table 1.

Comparison of two phenotypes of asthma based on the type of immune response [17,18,19].

T2-High	T2-Low
Overexpression of the immune type 2 ways (for example IL-4 and IL-13 genes)	Immune type 2 response is not overexpressed (overexpression of genes related with the inflammasome and superfamilies of interferon and tumour necrosis factor)
High sputum eosinophilia	High sputum neutrophilia
High exhaled nitric oxide fraction	-
High efficiency of omalizumab, mepolizumab, reslizumab and benralizumab	Low efficiency of omalizumab, mepolizumab, reslizumab and benralizumab