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. 2023 Aug 31;15(17):3808. doi: 10.3390/nu15173808

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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At 4 months post-surgery, there was a two-way interaction between the treatment and binge eating status groups in the inferior frontal gyrus in response to HEF (vs. LEF) cues. The RYGB NB group (vs. RYGB BE, NT BE, and NT NB participants) had the highest inferior frontal gyrus activation in response to HEF (vs. LEF) cues, whilst the NT NB participants (vs. RYGB BE, RYGB NB, and NT BE participants) had the lowest inferior frontal gyrus activation in response to HEF vs. LEF (which had a negative activation).