Table 3.
Regions of Interest (ROI) t-values for the four main hypothesized contrasts (see methods).
| ROI Coordinates (x, y, z) |
ROI Label | Baseline BE > NB Food > NF |
Post BE > NB Food > NF |
Post NT > RYGB BE > NB HEF > LEF |
Baseline > Post NT > RYGB HEF > LEF |
|---|---|---|---|---|---|
| −20, −64, 30 | Precuneus | 2.74 * | 2.76 * | 2.3 | −1.71 |
| 32, 36, 6 | Inferior Frontal Gyrus | 0.38 | 2.17 | 3.09 * | −1.14 |
| −6, 2, 36 | Dorsal Cingulate | 2.0 | 1.98 | 2.0 | −1.84 |
| 8, 58, 16 | Dorsomedial Prefrontal Cortex | 1.17 | −0.18 | 1.27 | −2.53 *a |
| 20, 38, 22 | Anterior Cingulate | 2.26 | 1.46 | 2.13 | −1.26 |
| −14, −22, 4 | Thalamus | 0.81 | 3.89 ** | 1.94 | −1.81 |
| 34, −70, 6 | Middle Occipital Gyrus | 1.16 | 0.41 | 3.06 * | −1.65 |
| 28, 22, 32 | Dorsolateral Prefrontal Cortex | 1.31 | 1.55 | 1.74 | −1.49 |
| −62, −12, 38 | Precentral Gyrus | 1.43 | 0.76 | 1.05 | −1.86 |
* Significant at p < 0.006 uncorrected. ** Significant at p < 0.05 corrected. Baseline and 4 months post-surgery BMIs were entered as covariates. a From baseline to 4 months post-surgery, the RYGB and NT groups had reduced activation in this region in response to High (vs. Low Energy Density) Food, whereas RYGB had an increase and NT had a decrease in response to Low (vs. High Energy Density) Food.