Table 2.

Associations of tissue R2_water with circulating markers of iron metabolism and dietary iron intake.

			Circulating Marker				Dietary Intake (mg/day)
Tissue R2water	Group	Model	Ferritin		Hepcidin		Total Iron		Haem Iron		Non-Haem
			DF	p-Value	DF	p-Value	DF	p-Value	DF	p-Value	DF	p-Value
Pancreas R2water
	Health	Model 1	0.36	0.13	0.87	0.04	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
		Model 2	<0.001	<0.001	0.67	0.10	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
		Model 3	<0.001	<0.001	0.62	0.12	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
	AP	Model 1	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	0.06	0.07	<0.001	<0.001
		Model 2	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	0.54	0.12	<0.001	<0.001
		Model 3	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	0.58	0.12	<0.001	<0.001
	CP	Model 1	2.00	<0.001	2.00	0.03	<0.001	<0.001	0.01	<0.001	0.72	0.08
		Model 2	2.00	0.01	2.00	0.07	<0.001	<0.001	0.86	0.12	0.63	0.11
		Model 3	2.00	0.01	2.00	0.04	<0.001	<0.001	0.90	0.13	0.65	0.11
Liver R2water
	Health	Model 1	5.33	0.01	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
		Model 2	5.32	0.02	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
		Model 3	5.15	0.02	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
	AP	Model 1	0.87	0.05	0.17	0.11	0.40	0.12	0.62	0.09	0.29	0.12
		Model 2	0.80	0.06	<0.001	<0.001	0.40	0.14	0.69	0.09	0.25	0.13
		Model 3	0.84	0.05	<0.001	<0.001	0.51	0.13	0.76	0.09	0.37	0.14
	CP	Model 1	1.35	0.01	<0.001	<0.001	<0.001	<0.001	0.98	0.03	<0.001	<0.001
		Model 2	1.42	0.03	<0.001	<0.001	<0.001	<0.001	0.97	0.05	<0.001	<0.001
		Model 3	1.43	0.04	<0.001	<0.001	<0.001	<0.001	1.22	0.02	<0.001	<0.001

Footnotes: Data are presented as degrees of freedom and p-values (from generalised additive model). Model 1: unadjusted. Model 2: adjusted for age, sex, and body mass index. Model 3: adjusted for age, sex, body mass index, and glycated haemoglobin. Statistically significant associations (p < 0.05) are in bold. Abbreviations: AP, acute pancreatitis; CP, chronic pancreatitis; DF, degrees of freedom.