Figure 5.

Effects of Mh-ME in HCl/EtOH-triggered gastritis-induced mice. (A,B) Mh-ME (100 and 200 mg/kg) was orally administered to mice, and acute gastritis was induced by 150 mM HCl/60% EtOH for 1 h. After sacrifice, pictures of inflammatory lesions in the stomach were collected, and the sizes of blood spots were quantitatively evaluated using ImageJ (ver. 1.8.0). (C,D) The mRNA expression levels of IL-1β and TNF-α from stomach lysate were examined by quantitative real-time PCR. (E) Phosphorylation levels of p50 and p65 from stomach lysates of mice were detected by Western blotting. All data from three independent experiments are represented as the mean ± SD value. ## p < 0.01 compared with the normal group; * p < 0.05 and ** p < 0.01 compared with the control group.