TABLE 2.
Relationship between the patterns of reactivity with VP4 NtMAbs and the G serotype of HRV specimens collected during two epidemic seasons, 1994–1995 and 1995–1996, in Mexico
| VP7 sero- typea | Season | No. (%) of specimens that reacted with the indicated MAbb
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| F45, 1A10 (Ac) | F45 (B) | 1A10 (C) | F45, 1A10, RV5 (D) | F45, RV5 (E) | 1A10, RV5 (F) | RV5 (G) | HS6 (H) | Negd | Total | ||
| G1 | 1994–1995 | 32 (40) | 30 (38) | 2 (3) | 3 (4) | 1 (1) | —e | — | — | 11 (14) | 79 |
| 1995–1996 | 45 (35) | 22 (17) | 3 (2) | 8 (6) | 4 (3) | — | — | — | 48 (37) | 130 | |
| G2 | 1994–1995 | — | — | — | — | — | 5 (46) | 5 (46) | — | 1 (9) | 11 |
| 1995–1996 | — | — | 1 (6) | — | — | 5 (28) | 9 (50) | — | 3 (17) | 18 | |
| G3 | 1994–1995 | 101 (57) | 11 (6) | 6 (4) | 14 (8) | 1 (1) | — | — | 1 (1) | 42 (24) | 176 |
| 1995–1996 | 2 (17) | 2 (17) | 3 (25) | — | — | — | — | — | 4 (33) | 11 | |
| G4 | 1994–1995 | — | — | — | — | — | — | — | — | 1 (100) | 1 |
| 1995–1996 | — | — | 2 (67) | — | — | — | — | — | 1 (33) | 3 | |
| Total | 1994–1995 | 133 (50) | 41 (15) | 8 (3) | 17 (6) | 2 (1) | 5 (2) | 5 (2) | 1 (0.4) | 55 (21) | 267 |
| 1995–1996 | 47 (29) | 24 (15) | 9 (6) | 8 (5) | 4 (3) | 5 (3) | 9 (6) | — | 56 (34) | 162 | |
a
The results for 141 viruses whose G serotype could not be identified are not included here.
b
The P serotypes of the viruses used to generate the VP4 Nt-MAbs are P1A for MAbs 1A10 and F45, P1B for MAb RV5, and P2A for MAb HS6.
c
For simplicity during their reference in the text, the VP4 MAb patterns found were designated A to H.
d
Neg, specimens that were not reactive with any of the MAbs used.
e
—, no specimen reacting with the indicated VP4 MAbs was detected.