Figure 3.

Protection effect against copper stress by T. esculenta extracts. (A) MTT reduction percentage when NIH/3T3 cell line was exposed to copper stress and was treated with leaves extracts (HF and IF). (B) MTT reduction percentage when the NIH/3T3 cell line was exposed to copper stress and was treated with fruit peel extracts (HC and IC). HF corresponds to the hydroethanolic extract obtained with the leaves, IF corresponds to the infusion extract obtained with the leaves, HC corresponds to the hydroethanolic extract obtained with the fruit peels, and IC corresponds to the infusion obtained with the fruit peels. The negative control (NC) corresponds to the culture medium only. The positive control (PC) represents a culture medium containing 25 µM CuSO₄ and 1 mM ascorbate. Values are expressed as mean ± standard deviation. # indicates statistical significance compared with the positive control (p < 0.001). ^a represents the statistically significant differences among treatments for the Tukey test (p < 0.05).