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. 2023 Sep 6;43(36):6249–6267. doi: 10.1523/JNEUROSCI.0247-23.2023

Figure 6.

Figure 6.

Increased responsiveness to psychostimulant in DAT-Cul3f/+ mice. A, Increased distance traveled by DAT-Cul3f/+ mice, shown as 5 min intervals during 10 min before and 60 min after cocaine injection (indicated by a red arrow). n = 13 mice per group. Cul3f/f + veh versus DAT-Cul3f/+ + veh, p = 0.0238, F(1,24) = 5.82; Cul3f/f + cocaine versus DAT-Cul3f/++ cocaine, p = 0.0018, F(1, 24) = 12.37; two-way ANOVA followed by Bonferroni's post hoc test. B, Increased total distance traveled by DAT-Cul3f/+ mice within 60 min after cocaine injection. n = 13 mice per group. Cul3f/f + veh versus DAT-Cul3f/+ + veh, p = 0.0178, t(22.18) = 2.561; Cul3f/f + cocaine versus DAT-Cul3f/++ cocaine, p = 0.0025, t(19.92) = 3.454; unpaired t test. Data are mean ± SEM. *p < 0.05. **p < 0.01. ***p < 0.001.