Figure 11.

Behaviors during swim stressor in Phase 2 mice. Mice in Phase 2 assigned to swim stress experienced an acute 6 min swim stressor 4 wks before undergoing Cued (A,C) or Context (B,D) fear conditioning. Female (A-B) wildtypes are represented by teal squares, and female hetero-zygotes are represented by blue diamonds. Male (C-D) wildtypes are represented by orange squares, and male heterozygotes are represented by yellow diamonds. Data are the amount of time in seconds spent swimming, immobile, or climbing; or the amount of time until the first bout of immobility (i.e., latency). *p=0.049, *p=0.043 (left to right, panel C) indicate difference between heterozygous and wildtype within same sex for the same swim behavior. ^⊙p=0.032, ^⊙p=0.030, ^⊙⊙p=0.006, ^⊙⊙p=0.003 (left to right, panel D) indicates difference between sexes within same genotype and swim behavior.