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[Preprint]. 2023 Aug 29:2023.08.28.555225. [Version 1] doi: 10.1101/2023.08.28.555225

Figure 6. Reproducibility and Statistical Power for Proteograph Workflow in large-scale Discovery Proteomics Studies.

Figure 6.

(A) Experimental design of the reproducibility study. (B) Peptide level CV within and across plates, Proteograph SP100 automation instruments, and days of LC-MS analysis. (C) Experimental design of cohort study. (D) Peptide CV within and across LC-MS/MS instruments. (E) Statistical power analysis for a 200-sample, 1,000 injections cohort study detecting fold-change difference with 5% FDR and a power of 0.8.