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Western immunoblot, stained with MAb F89/160.1.5, of PK-treated preparation from brain of a sheep with scrapie, showing PK-resistant glycopeptides characteristic of PrP-Sc (lane 1). No PrP-Sc was demonstrated in brain collected from a sheep with no known exposure to scrapie (lane 2) processed under identical conditions. Bars in the left lane correspond to molecular size markers (in kilodaltons).
