Table 4:

En masse test of concordance of effect directions between genetic variants identified for ANX (condFDR) and corresponding variants in independent GWAS of anxiety disorders from the Finnish population (FINNGEN).

CondFDR Phenotype pairs	ANX-loci (n)	SNPs (n) in the replication dataset	SNPs (n) with concordant effects	p-value*
ANX | MD	81	79	69 (87%)	2.77E-12
ANX | BIP	61	60	49 (82%)	3.78E-07
ANX | SCZ	105	105	88 (84%)	4.98E-13
ANX|ADHD	57	57	47 (82%)	3.76E-07

GWAS: Genome-wide association study, SNP: Single nucleotide polymorphism, FDR: False discovery rate, ANX: Anxiety symptoms, MD: Major depression, BIP: Bipolar disorder, SCZ: Schizophrenia, ADHD: Attention deficit hyperactivity disorder,

^*one-sided binomial test