Table 4.
Differences in the associations of risk factors with WMH between Whites and Asians
| Risk Factors | WMH measure | Whites | Asians | ||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| β | CI lower | CI upper | β | CI lower | CI upper | ||
|
| |||||||
| Hypertension | WBWMH | 0.074** | 0.031 | 0.116 | 0.016 | −0.084 | 0.115 |
| Stroke | WBWMH | 0.124** | 0.029 | 0.220 | 0.006 | −0.127 | 0.139 |
| Stroke | PVWMH | 0.083 | −0.002 | 0.176 | 0.001 | −0.127 | 0.129 |
| Stroke | DMWH | 0.176* | 0.021 | 0.331 | 0.050 | −0.137 | 0.230 |
| Hypercholesterolemia | WBWMH | −0.005 | −0.044 | 0.034 | −0.081* | −0.164 | −0.002 |
| Hypercholesterolemia | PVWMH | −0.019 | −0.042 | 0.036 | −0.084* | −0.168 | −0.001 |
| Hypercholesterolemia | DWMH | −0.003 | −0.076 | 0.038 | −0.061 | −0.177 | 0.055 |
The table shows regression coefficients for risk factors in White and Asian subsamples. Only factors for which an interaction term between risk factor and ethnicity had p<0.1 are included.
*
- p <0.05
**
- p <0.01.
CI - 95% confidence interval. WBWMH – whole brain white matter hyperintensity; PVWMH –periventricular white matter hyperintensity, DWMH –deep white matter hyperintensity.