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. 2023 May 30;13(5):479–488. doi: 10.1016/j.jtcme.2023.05.003

Fig. 1.

Fig. 1

Effects of VTT-S-95 E E on the changes of blood glucose. (A) Schematic protocols of animal experiments on simulations of postprandial blood glucose regulations in healthy ICR mice by oral glucose tolerance test (OGTT). Sample was administered orally 30 min before the glucose loads (2.5 g/kg of body weight, red arrow). (B) Effects of oral administration of VTT-S-95 E E (100 mg/kg, blue arrow) on the changes of blood glucose. The distilled water was used instead of sample additions as the blank. (C) The HPLC chromatograms of VTT-S-95EE, and the structures of hopeaphenol (1), vitisin A (2), and vitisin B (3). The identified compounds included resveratrol (37.05 min), (1) (43.51 min), (+)-ε-viniferin (resveratrol dimer, 46.95 min), (2) (52.77 min), and (3) (61.22 min). For OGTT in the healthy ICR mice, the difference between the test sample and the blank group at the same time point was statistically compared by the Student t-test when P < 0.05 (∗), or P < 0.01 (∗∗), or P < 0.001 (∗∗∗).