Table 5.
Univariate analysis of factors affecting the treatment efficacy
| Overall response Group (n=81) | Ineffective Group (n=17) | χ2/t | P | |
|---|---|---|---|---|
| Gender | 0.760 | 0.383 | ||
| Male | 48 (59.26) | 12 (70.59) | ||
| Female | 33 (40.74) | 5 (29.41) | ||
| Age of onset (years) | 4.2±1.3 | 4.3±1.2 | 0.771 | 0.292 |
| Average course of disease (days) | 5.8±3.4 | 8.2±2.9 | 2.708 | 0.008 |
| Admission body temperature (°C) | 38.4±0.6 | 38.8±0.6 | 2.499 | 0.014 |
| Clinical manifestations | ||||
| Fever | 72 (88.89) | 14 (82.35) | 0.559 | 0.455 |
| Isthmitis | 53 (65.43) | 16 (94.12) | 5.549 | 0.019 |
| Cervical lymph node enlargement | 65 (80.25) | 13 (76.47) | 0.123 | 0.725 |
| Place of residence | 0.363 | 0.547 | ||
| Rural area | 25 (30.86) | 4 (23.53) | ||
| Urban area | 56 (69.14) | 13 (76.47) | ||
| Admission to school or not | 2.106 | 1.451 | ||
| Yes | 29 (35.80) | 3 (17.65) | ||
| No | 52 (64.20) | 14 (82.35) | ||
| Admission IgA | 4.47±1.32 | 5.28±0.74 | 2.444 | 0.016 |
| Admission IgG | 12.88±3.11 | 14.75±2.19 | 2.355 | 0.021 |
| Admission IgM | 1.51±0.32 | 1.73±0.30 | 2.603 | 0.011 |
| Admission white blood cell count | 16.20±3.39 | 18.47±2.09 | 2.651 | 0.009 |
| Admission lymphocyte proportion | 47.54±6.22 | 52.04±4.08 | 2.851 | 0.005 |
| Treatment mode | 5.041 | 0.025 | ||
| Ribavirin | 33 (40.74) | 12 (70.59) | ||
| Acyclovir | 48 (59.26) | 5 (29.41) |
Notes: IgG: immunoglobulin G, IgA: immunoglobulin A, IgM: immunoglobulin M.