Table 3.
The molecular docking verification analysis
| Target Gene | Target Protein | PDB ID | The Lowest Vina Score |
|---|---|---|---|
| SRC | Proto-oncogene tyrosine-protein kinase Src | 3D7T | -9.7 |
| MAPK1 | Mitogen-activated protein kinase 1 | 6G54 | -10.0 |
| HSP90AA1 | Heat shock protein HSP 90-alpha | 5NJX | -7.4 |
| AKT1 | RAC-alpha serine/threonine-protein kinase | 2UZR | -7.9 |
| PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | 7JVN | -9.1 |
| ESR1 | Estrogen receptor | 4XI3 | -8.3 |
| EGFR | Epidermal growth factor receptor | 3IKA | -8.7 |
| RHOA | Transforming protein RhoA | 1TXD | -7.3 |
| JAK2 | Tyrosine-protein kinase JAK2 | 6E2Q | -9.5 |
| MAPK14 | Mitogen-activated protein kinase 14 | 5ETI | -8.1 |