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. 2023 Aug 15;15(8):5292–5303.

Table 3.

Intraprocedural pulmonary and cardiac adverse events

Group MAC (n=120) Group GA1 (n=120) Group GA2 (n=120) Statistical significance
Overall complication (n, %) 45 (37.5%) 23 (19.2%) 21 (17.5%) < 0.001
Pulmonary events (n, %) 25 (20.8%) 0 0 < 0.001
Hypoxemia 25 (20.8%) 0 0 < 0.001
The use of airway maneuvers 25 (20.8%) 0 0 < 0.001
    Jaw thrust 10 (7.5%) 0 0 < 0.001
    Nasal airway 4 (3.3%) 0 0 0.036
    Bag mask ventilation 6 (4.2%) 0 0 0.004
    Endotracheal intubation 5 (1.7%) 0 0 0.012
Regurgitation 0 0 0 N/A
Aspiration 0 0 0 N/A
Laryngospasm 0 0 0 N/A
Bronchospasm 0 0 0 N/A
Chest wall rigidity 0 0 0 N/A
Cardiac Events (n, %) 20 (16.7%) 23 (19.2%) 21 (17.5%) 0.911
Hypertension 4 (3.3%) 0 0 0.036
Hypotension 8 (6.7%) 11 (9.2%) 9 (7.5%) 0.829
New-onset arrhythmia or worsening of pre-existed arrhythmia 8 (6.7%) 12 (10.0%) 12 (10.0%) 0.605
    Premature atrial contractions 2 (1.7%) 5 (4.2%) 4 (3.3%) 0.639
    Premature ventricular contractions 2 (1.7%) 2 (1.7%) 0 0.552
    Bradycardia 4 (3.3%) 5 (4.2%) 8 (6.7%) 0.548
    Tachycardia 0 0 0 N/A
    ST-segment changes 0 0 0 N/A
Major adverse cardiac events 0 0 0 N/A
    Cardiac arrest 0 0 0 N/A
    Shock 0 0 0 N/A
    Acute coronary syndrome 0 0 0 N/A

Defined criteria: Hypoxemia (SpO2 < 90%); hypertension (MAP increase > 40% and a MAP > 110 mmHg); hypotension, systolic pressure < 90 mmHg or mean pressure < 60 mmHg; tachycardia, heart rate > 120 beats/min; bradycardia, heart rate < 55 beats/min. Data presented as n (%) of patients. Categorical data were compared using Pearson’s chi-squared test or Fisher’s exact test. MAP, Mean artery pressure.