Comparisons between the baseline concentration of 40 chemokines in responders and non-responders. (A) Unsupervised hierarchical clustering of baseline concentrations of 40 chemokines in patients (n = 50). High concentration levels are shown in red, while low concentration levels are shown in blue. Each column represents a patient and each row represents a chemokine. (B) Baseline serum concentration score of MIF and TNF-α in R and NR groups. R, responder; NR, non-responder. *p < 0.05, **p < 0.01, ***p < 0.001. (For interpretation of the references to color in the text, the reader is referred to the web version of this article.)