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. 2023 Aug 28;26(10):107756. doi: 10.1016/j.isci.2023.107756

Table 1.

CircMAPK9 expression in the obese sample

Clinical or molecular feature CircMAPK9 down-expression (35) CircMAPK9 over-expression (35) P
Age (y) 33 (29, 39) 30 (26, 40) 0.445
BMI (kg/m2) 35.26 ± 4.92 41.66 ± 7.28 < 0.001
HbA1c (%) 5.9 (5.5, 6.25) 6 (5.55, 6.55) 0.441
HOMA-IR 3.11 (2.21, 4.22) 4.4 (3.28, 5.69) 0.004
TC (mmol/L) 4.46 (4.06, 5.4) 4.64 (4.29, 5.37) 0.356
TG (mmol/L) 1.24 (0.86, 1.96) 1.81 (1.36, 3) 0.018
LDL-C (mmol/L) 2.52 (2.33, 3.41) 3.11 (2.71, 3.45) 0.096
HDL-C (mmol/L) 1.19 (1.02, 1.36) 1.06 (0.96, 1.24) 0.055
Hypertension 51% (18/35) 57% (20/35) 0.810
Type Ⅱ Diabetes 34% (12/35) 66%(23/35) 0.017
Hyperlipemia 34% (12/35) 51% (18/35) 0.227
Hyperuricemia 17% (6/35) 49% (17/35) 0.011
OSAS 23% (8/35) 29% (10/35) 0.784
NAFLD 60% (21/35) 91% (32/35) 0.005
Cholelithiasis 6% (2/35) 9% (3/35) 1.000

BMI, Body mass index; HbA1c, Glycated hemoglobin; HOMA-IR, Homeostasis model assessment of insulin resistance; TC, Total cholesterol; TG, Triglycerides; LDL-C, Low-density lipoprotein cholesterol; HDL-C, High-density lipoprotein cholesterol; OSAS, Obstructive sleep apnea syndrome; NAFLD, Non-alcoholic fatty liver disease.