Table 1.
Inventory list of key components from signal transduction pathways in Tetranychus
| Class/function | Name | Duplication |
|---|---|---|
|
| ||
| TGF-beta | ||
| Ligand | dpp | |
| actbeta | Duplication (2) | |
|
Gbb
myo |
Duplication (2) | |
| Extracellular modifiers | tlk | Duplication (4) |
|
sog
fs |
Duplication (2) | |
| Type I receptor | babo | |
|
tkv
Sax |
Duplication (2) | |
| Type II receptor | put | Duplication (2) |
| R-SMAD | Mad | |
| R-SMAD | Smox | |
| Co-SMAD (common) | Med | |
| Transcription factor |
Rbf
nej shn snoN |
|
| Smad binding |
fuss (CORL)
Rocla cul/linl9 Sara |
Duplication (2) |
| lack | Duplication (2) | |
| (absences) |
DAW,
ADMP, scw, mav, BMP-10, wit, tld |
|
| Wnt | ||
| Ligand |
Wnt4
Wnt5 |
|
|
Wnt6
Wnt8 Wnt 16 WntA |
Duplication (3) | |
| Transmcmbranc receptor | Vang | Duplication (2) |
| fz | Duplication (2) | |
|
fz2
fz4 arr |
Duplication (2) | |
| Activated by frizzled | dsh | Duplication (2) |
| Arm destruction complex |
APC
sgg |
Duplication (2) |
| Downstream effector | arm | Duplication (3) |
| (β-Catenin binding | pont | |
| Antagonist of β-catenin | Cby | |
| pan | Duplication (3) | |
| Transcription factor | CtBP | |
| Scaffolding protein | ebi | Duplication (2) |
| Ligand modifier | wls | |
| por | ||
| shf | ||
| Wnt-protein binding | dlp | |
| (absences) | wg, wnt2, wnt3, wnt7, wnt9, wnt 10, wnt11, Axn, pygo, Igs, nkd | |
| Notch | ||
| Ligand |
Dl
Ser |
|
| Transmcmbranc receptor | N | Duplication (4) |
| Receptor modifier |
O-fut
fng |
|
| Protease | Fur1 | Duplication (2) |
| Mctalloprotcasc | kuz | |
| γ-Secrctasc complex |
Psn
pen-2 nct |
|
| Aph01 | Duplication (2) | |
| Transcription factor | Su(H) | Duplication (3) |
| gro | Duplication (2) | |
| nub | Duplication (2) | |
| (absences) | Tace, dx, H, mam, E(spl) | |
| RTK | ||
| EGF | ||
| Ligand |
spi
vn |
|
| Transmcmbranc receptor | EGFR | |
| kek-1 | ||
| kek-3 | Duplication (2) | |
| EGFR inhibitor | aos | Duplication (2) |
| (absences) | grk, Km, Yan | |
| FGF | ||
| Transmcmbranc receptor | htl | Duplication (2) |
|
sgl
sfl |
||
| ECM component | trol | |
| (absences) | bnl, btl, pyr, ths, sty | |
| Scvenless/MAPK | ||
| Transmcmbranc receptor | sev | |
|
drk
Sos |
||
| Rasl | Ras85D | |
| MAPKKK (RAF) | phi | |
| MAPKK (MEK) |
Dsor1
hep lic |
|
| MAPK |
rl
p38b |
|
| (absences) | boss | |
| JAK-STAT | ||
| Receptor | Dome | |
| JAK | hop | |
| STAT | Stat92E (mrl) | Duplication (2) |
| (absences) | os, upd2, upd3 | |
| Hh | ||
| Ligand | Hh | |
| Transmembrane receptor |
ptc
smo mgl |
|
| Transcription factor | ci | |
| Repressor | Su(fu) | Duplication (2) |
| (absences) | cos, fu | |
TGF-beta transforming growth factor-β, RTK receptor tyrosine kinase, EGF epidermal growth factor, EGFR epidermal growth factor receptor, FGF fibroblast growth factor, ECM extracellular matrix, MAPK mitogen-activated protein kinase, JAKSTAT Janus kinase/signal transducers and activators of transcription, Hh hedgehog