Table 2.

Associations with the risk of hepatocellular carcinoma

SNP	Number of studies included	Total participants	Genetic Model	Effect estimates, OR (95%CI); p value
-1082 A/G	9 (5 Asian group, 4 non-Asian group)	3089		Overall	Asian group	Non-Asian group
			Dominant	0.85 (0.70–1.03) [p:0.09]	1.01 (0.79–1.29) [p:0.95]	0.62 (0.45–0.86) [p:0.004]
			Recessive	1.10 (0.79–1.54) [p:0.56]	1.30 (0.80–2.13) [p:0.29]	0.97 (0.62–1.52) [p:0.88]
			Heterozygous)	0.82 (0.67–0.99) [p:0.04]	0.97 (0.75–1.25) [p:0.65]	0.60 (0.43–0.85) [p:0.007]
			Homozygous	0.91 (0.64–1.30) [p:0.61]	1.20 (0.72–1.99) [p:0.65]	0.71 (0.43–1.17) [p:0.51]
			Allelic (	0.92 (0.80–1.07) [p:0.28]	1.05 (0.86–1.29) [p:0.63]	0.80 (0.64–0.99) [p:0.04]
-819 T/C	8 (6 Asian group, 2 non-Asian group)	3332		Overall	Asian group	Non-Asian group
			Dominant	1.25 (1.05–1.48) [p:0.37]	1.19 (0.98–1.45) [p:0.27]	1.47 (1.02–2.13) [p:0.032]
			Recessive	1.10 (0.81–1.50) [p:0.]	0.96 (0.74–1.26) [p:0.]	1.99 (1.03–3.86) [p:0.]
			Heterozygous	1.20 (1.00-1.43) [p:0.73]	1.19 (0.97–1.46) [p:0.49]	1.23 (0.82–1.84) [p:0.93]
			Homozygous	1.17 (0.80–1.72) [p:0.37]	0.97 (0.65–1.44) [p:0.12]	2.18 (1.13–4.23) [p:0.03]
			Allelic	1.08 (0.89–1.32) [p:0.35]	0.98 (0.81–1.19) [p:0.11]	1.59 (0.96–2.63) [p:0.64]
-592 A/C	11 (10 Asian group, 1 non-Asian group)	7516		Overall	Asian group	Non-Asian group
			Dominant	0.90 (0.68–1.18) [p:0.44]	0.86 (0.63–1.16) [p:0.32]	1.29 (0.82–2.03) [p:0.27]
			Recessive TT vs. CT	0.89 (0.72–1.11) [p:0.31]	0.86 (0.69–1.08) [p:0.2]	1.45 (0.75–2.78) [p:0.26]
			Heterozygous	0.96 (0.75–1.22) [p:0.31]	0.93 (0.71–1.21) [p:0.57]	1.21 (0.75–1.96) [p:0.43]
			Homozygous	0.93 (0.77–1.12) [p:0.43]	0.91 (0.75–1.10) [p:0.33]	1.32 (0.66–2.63) [p:0.44]
			Allelic	0.90 (0.76–1.08) [p:0.25]	0.87 (0.72–1.05) [p:0.15]	1.26 (0.91–1.74) [p:0.17]

Bold indicates significant at p value < 0.05. CI: Confidence interval; OR: Odds ratio: