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. 2023 Sep 8;23:842. doi: 10.1186/s12885-023-11323-1

Table 3.

False positive report probability power and value

Genetic model OR
(95%CI)
FPRP
P value Statistical power Prior probability
0.25 0.1 0.01 0.001
-1082 A/G
Dominant
Non-Asian 0.62 (0.45–0.86) 0.004 0.321 0.038 0.105 0.564 0.929
Heterozygous)
Overall 0.82 (0.67–0.99) 0.039 0.982 0.106 0.263 0.797 0.975
Non-Asian 0.60 (0.43–0.85) 0.004 0.267 0.043 0.12 0.6 0.938
Allelic
Non-Asian 0.80 (0.64–0.99) 0.04 0.953 0.112 0.275 0.806 0.977
-819 T/C
Dominant
Non-Asian 1.47 (1.02–2.13) 0.042 0.543 0.188 0.409 0.884 0.987
Recessive
Non-Asian 1.99 (1.03–3.86) 0.042 0.202 0.383 0.651 0.954 0.995
Homogenous
Non-Asian 2.18 (1.13–4.23) 0.021 0.134 0.321 0.587 0.940 0.994

FPRP: False positive report probability. Statistical power is the power to detect an odds ratio of 1.5 with the genetic variant (or, 0.67 = 1/1.5 for protective effect). The results in bold implies noteworthiness of association at 0.2 level by FPRP. Not performed FPRP test for IL10 (-592 A/C) as there was no significant association with hepatocellular carcinoma risk (See Table 2)