Table 3.
False positive report probability power and value
| Genetic model | OR (95%CI) |
FPRP | |||||
|---|---|---|---|---|---|---|---|
| P value | Statistical power | Prior probability | |||||
| 0.25 | 0.1 | 0.01 | 0.001 | ||||
| -1082 A/G | |||||||
| Dominant | |||||||
| Non-Asian | 0.62 (0.45–0.86) | 0.004 | 0.321 | 0.038 | 0.105 | 0.564 | 0.929 |
| Heterozygous) | |||||||
| Overall | 0.82 (0.67–0.99) | 0.039 | 0.982 | 0.106 | 0.263 | 0.797 | 0.975 |
| Non-Asian | 0.60 (0.43–0.85) | 0.004 | 0.267 | 0.043 | 0.12 | 0.6 | 0.938 |
| Allelic | |||||||
| Non-Asian | 0.80 (0.64–0.99) | 0.04 | 0.953 | 0.112 | 0.275 | 0.806 | 0.977 |
| -819 T/C | |||||||
| Dominant | |||||||
| Non-Asian | 1.47 (1.02–2.13) | 0.042 | 0.543 | 0.188 | 0.409 | 0.884 | 0.987 |
| Recessive | |||||||
| Non-Asian | 1.99 (1.03–3.86) | 0.042 | 0.202 | 0.383 | 0.651 | 0.954 | 0.995 |
| Homogenous | |||||||
| Non-Asian | 2.18 (1.13–4.23) | 0.021 | 0.134 | 0.321 | 0.587 | 0.940 | 0.994 |
FPRP: False positive report probability. Statistical power is the power to detect an odds ratio of 1.5 with the genetic variant (or, 0.67 = 1/1.5 for protective effect). The results in bold implies noteworthiness of association at 0.2 level by FPRP. Not performed FPRP test for IL10 (-592 A/C) as there was no significant association with hepatocellular carcinoma risk (See Table 2)