TABLE 2.
MICs of antibiotics for clinical isolates of B. wadsworthia, as determined by agar and broth microdilution methods and Etest
| Antibiotic | Strain | MIC (μg/ml) by:
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Agar dilution (CFU/spot)
|
Broth microdilution (CFU/well)
|
Etest (agar)
|
|||||||
| 104 | 105 | 106 | 105 | 106 | 107 | Brucella HK | BBE | ||
| Ampicillin | NBW1 | 16 | >128 | >128 | 8 | 8 | 8 | 1.5 | 3 |
| NBW2 | 16 | >128 | >128 | 16 | 16 | >128 | 4 | 4 | |
| NBW3 | 16 | >128 | >128 | 16 | 16 | >128 | 16 | 12 | |
| NBW4 | 16 | >128 | >128 | 8 | 16 | 16 | 4 | 3 | |
| NBW5 | 16 | >128 | >128 | 16 | 16 | 16 | 12 | 8 | |
| NBW6 | 16 | >128 | >128 | 8 | 8 | 8 | 4 | 4 | |
| Sulbactam- | NBW1 | 16 | >128 | >128 | 4 | 4 | 4 | 0.125 | 0.125 |
| ampicillin | NBW2 | 16 | >128 | >128 | 8 | 8 | 8 | 1.5 | 0.75 |
| NBW3 | 2 | >128 | >128 | 8 | 8 | 8 | 0.125 | 0.125 | |
| NBW4 | 16 | >128 | >128 | 4 | 4 | 16 | 0.75 | 0.25 | |
| NBW5 | 2 | >128 | >128 | 4 | 8 | 8 | 0.25 | 0.125 | |
| NBW6 | 2 | 128 | >128 | 4 | 4 | 4 | 0.75 | 0.38 | |
| Ceftizoxime | NBW1 | 16 | >128 | >128 | 1 | 1 | 2 | 8 | 4 |
| NBW2 | >128 | >128 | >128 | 0.5 | 0.25 | 2 | 48 | 12 | |
| NBW3 | 16 | >128 | >128 | 1 | 0.5 | 0.5 | 3 | 1.5 | |
| NBW4 | >128 | >128 | >128 | 1 | 2 | 2 | 12 | 8 | |
| NBW5 | 32 | >128 | >128 | 0.5 | 0.5 | 2 | 48 | 12 | |
| NBW6 | 16 | >128 | >128 | 1 | 0.5 | 0.5 | 8 | 3 | |
| Imipenem | NBW1 | 0.25 | 0.25 | >128 | 16 | 32 | 32 | 0.125 | 0.5 |
| NBW2 | 0.125 | 0.25 | >128 | 8 | 16 | 64 | 0.125 | 0.25 | |
| NBW3 | 0.25 | 0.25 | >128 | 8 | 16 | 64 | 0.125 | 0.19 | |
| NBW4 | 0.125 | 0.25 | >128 | 32 | 32 | 64 | 0.125 | 0.19 | |
| NBW5 | 0.25 | 0.25 | >128 | 16 | 128 | 128 | 0.125 | 0.25 | |
| NBW6 | 0.06 | 0.125 | >128 | 32 | 32 | 32 | 0.094 | 0.38 | |
| Clindamycin | NBW1 | 0.125 | 0.25 | >128 | ≦0.06 | ≦0.06 | 0.25 | 0.064 | 0.125 |
| NBW2 | 0.25 | 0.25 | >128 | ≦0.06 | ≦0.06 | 0.25 | 0.094 | 0.064 | |
| NBW3 | 0.25 | 0.25 | >128 | 0.25 | 0.25 | 0.5 | 0.064 | 0.064 | |
| NBW4 | 0.25 | 0.25 | >128 | ≦0.06 | 0.125 | 0.125 | 0.125 | 0.064 | |
| NBW5 | 0.125 | 0.25 | >128 | 0.25 | 0.25 | 0.25 | 0.047 | 0.047 | |
| NBW6 | 0.25 | 0.25 | >128 | ≦0.06 | 0.25 | 0.25 | 0.125 | 0.19 | |