Table 1. Impact of altered thyroid hormone on skin pathophysiology.

Hypothyroidism	Thyrotoxicosis
1- Epidermal alterations:	Epidermal alterations:
Coarse, scaly, thin, skin	Thin, smooth skin
Hair and Nail alterations	2- Hair and Nail alterations
Alopecia, loss of lateral third of eyebrows	Alopecia
Coarse, dry, brittle hair	Fine hair
Coarse, brittle, dull, thin nails	Soft, shiny, friable nails (Plummer’s nails, onycholysis)
3-Sweat gland alterations
Xerosis (dry skin), decreased sweating
4-Dermal alterations
Myxedema (non-pitting edema), carotenemia
Edema (face, hands, eyelids), pallor